SU 2021 Customisation disappears after a couple of days

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Yes having correct profile info would certainly help ( I just saw ‘ms’ somewhere at the time and ‘trays’ on Mac are called inspector panels.)

The procedure and working are the same.

Things can go bad when not installed, however.
Also check this thread:

Best thing to do is to quit all instances of SketchUp.

Remove docked icons (drag them up).
Remove disk images from the desktop as well (little gray harddisc pictures)

Remove SketchUp 2021 folder (if exists) from the Application folder.

Empty trashbin.
(Might want to reboot at this point)

Be sure to have the latest download.
Double clicking will mount the right disc image on the desktop and pop up a window with two icons, a SketchUp logo and the Application folder logo.

Drag the SketchUp icon into that of the application folder.
Wait for it to have finished (1.7 GB)
Close panel.
Remove disc image from desktop.
Go to Application folder and start SketchUp.
Dock the appearing icon.
Make changes to the UI.

Close SketchUp.

From then on, double clicking on a SketchUp file or opening from the dock icon or Application folder will show your latest changes to the UI.