Page setup when printing in layout or pdf

All is well with model and sending to layout. viewport setups work well, dimensions, notations etc.
I do have a large format printer, when I do page setup, select tabloid, print preview my page orientation moves up, right, left and bottom margins become large and objects are cutoff.
When I export to PDF, orientation is better, but must be reduced in size to fit, not to scale.
Also, when I move back and forth between print preview and layout file it appears to occasionally change scene style and create colored blocks in the background.
Thanks in advance!

Dropbox

Have you tried to export and then print the PDF?