Instead of being limited to a single letter or a control key for a shortcut, expand the choices to multiple letters.
This was poached from @gsharp
So similarly in Autocad [which has very good keyboard hotkey tools]
single letter for most common command
same letter twice for second most common command and
same letter 3 times for the related dialogue box
eg
L = LINE COMMAND
LL = POLYLINE COMMAND
LLL = LAYER DIALOGUE BOX
D = DISTANCE
DD = DIMENSION
DDD = DIMENSION DIALOGUE BOX