Like a Version... SketchUp & Layout open files in older version as default

I’m having an issue with SketchUp and Layout files attempting to open in version 2019 rather than version 2020 and now 2021. I know this topic has been touched on before, but I’ve tried all of the previous recommendations and now plan to uninstall and reinstall 2021, with the hope that it will work. Presumably, installing a new version will cause the files to open in that version. I’ve installed two new versions since 2019 and still have the issue.
Question: By uninstalling and reinstalling version 2021, will I lose all of the 2021 settings that I have in place to this point?