Hi blackdogSUP,
This sounds like it could be related to a toolbar or menu that is being displayed somewhere outside your visible screen and not visible for you to select.
We could start by clearing your preferences for LayOut by browsing to c:\Users(your user name)\AppData\Roaming\SketchUp\SketchUp 2018\LayOut
Rename the LayOut folder to LayOut2
Relaunch LayOut and see if you can access it normally. - Please let me know if you are still having trouble
Also we have an issue with 2018 when trying to double-click to launch LayOut.
See this thread Double click file open - Layout 2018 BUG? - #5 by paolodanielli