Those are all great suggestions. I’ll sum up what I would suggest starting with a potential fix followed by maintenance suggestions. The first two only apply to Windows systems.
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Materials Window - A painfully long start-up time is an issue experienced on some systems and we have been looking at very closely these last few months and we are working on a permanent fix. In the meantime, we have discovered a significant difference in load times when the Materials window is kept contracted and only expanded when access to Materials is needed. Please try testing this out and seeing if it makes a difference for you. On a related note, we have also heard of slowdowns attributed to an open Component window and also an open Outliner window.
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Driver Updates - Windows likes to conduct regular updates. To match those updates, I always recommend installing the absolute latest version of your video card drivers and keeping them updated on a regular basis. You can always rollback an unstable driver release.
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File Location - LAN connectivity was mentioned above. We always recommend storing your live files (files, on which, you are actively working) on your local drive and that the save path is NOT being actively synched to the cloud (in other words, if you are using a backup service like Dropbox, make sure it is not trying to synchronize the folder you are working from). Files saved to network shares or cloud storage stand a higher chance of corruption that is increased with larger files and slower or high traffic networks. If you want to ensure a secure backup of your work, I would recommend scheduling an after-hours backup of the save path or saving locally then dragging a copy to your network drive.
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Extensions - I’m not sure that I’ve seen slow load times attributed to Extensions, but I do like to recommend installing all extensions from the Extension Warehouse (when available). When doing so, make sure the extension says it is compatible with your current version of SketchUp. Holding on to that old 2016 extension to use with the latest SketchUp can result in anomalies.
Let us know what helps if any of it does.
Cheers!
-guz