When creating spheres what does this warning mean? Is it going to bite me on the back later on?

[yzj9s6hcpx]

[mihai.s]

The path it’s tilted, and not perpendicular with the shape

[colin]

What mihai.s showed also happens if the shape to follow is not centered with the profile. In your screenshot’s case, if the circle to follow had its center on the origin, and the circle to extrude was centered on green and red, there would have been no error message.

[yzj9s6hcpx]

Thanks for your help, it makes clear sense now