Do you normally have profiles turned on? That adds a lot of workload to your new machine.
You could check in the NVIDIA control panel PhysX settings - which GPU is running the monitor?
Is SU set to run with the NVIDIA GPU in the 3D settings?
With laptops, you can get intel GPU’s running monitors and the dedicated GPU trying to run the 3D software which doesn’t seem to coordinate perfectly. Adding external monitors adds to the difficulties.