I used to have quite a few problems of this kind with Layout before I upgraded to a more powerful computer. Changing the rendering to Hybrid was a favourite source of crashes. A lot of it was unpredictable. Some files were fine, or fine for a while, and then LO just seemed to decide arbitrarily not to play ball any longer.
Can’t say this is your problem as you don’t say in your profile what machine you are using. But it may have a bearing.