Most of our users have GPU’s in the mid-high level range.
We noticed some users work with Sketchup just fine with 1-2 plugins but we have a few users with a decent amount of plugins.
As the number of extensions increases the time for them all to load will increase which will increase startup time. It’s possible that there are some installed extensions that have observers running and that could slow things down.
Can’t really tell much from a screenshot of some toolbars.
Another thing that might come into play is general model management. Maybe some users are doing a better job of managing their models to keep them streamlined.