No not including keyboard. The mouse buttons are mapped to keyboard buttons yes but I don’t use the keyboard.
I use a bit less than 60 I think to be more precise it’s like 48 right now. Basically if you combo key buttons so there are 2 individual buttons on the space mouse and I can use 2 or even 3 buttons as dedicated combo keys from my mmo mouse (combo keys, alt, control, shift, cntrl+alt, cntrl+shift, etc, etc) I can get a lot of tool options, probably over a 100 if I really needed or wanted to. I generally use about 30 on the daily. Once in awhile I have to remind myself about which button is which.
The screenshot shows the list of plugins I use regularly (most of them regularly anyways).